| 1. | 1/30/2008 9:38:00 PM | that is not a correct interpretation of the data. Vytorin did lower total chol more than simva alone in the study |
| 2. | 1/30/2008 9:47:00 PM | The study showed lower cholesterol but no benefit on carotid IMT |
| 3. | 1/30/2008 10:08:00 PM | This is wrong. Zetia + zocor lowers cholesterol better than zocor alone |
| 4. | 1/30/2008 10:22:00 PM | this statement is not correct. It(vytorin) did lower LdL cholesterol more than simvastatin alone |
| 5. | 1/30/2008 10:52:00 PM | The trial did not say it wasn't effective in lowering cholesterol; it was not effective in reducing carotid intimal thickening; no difference in MACE events |
| 6. | 1/30/2008 10:53:00 PM | The trial did not say it wasn't effective in lowering cholesterol; it was not effective in reducing carotid intimal thickening; no difference in MACE events |
| 7. | 1/31/2008 4:51:00 PM | what? "No more effective"? in reducing carotid plaque or lowering the LDL. For sure it lowers the LDL |
| 8. | 2/1/2008 3:19:00 AM | I have not prescribed vytorin |
| 9. | 2/1/2008 5:42:00 PM | Your statement is wrong. Zetia + Zocor DID lower LDL more than Zocor alone. Statistical difference in the level of LDL cholesterol reached bewteen the two arms of study. Neither arm slowed down progression or caused regression, as would be fully expected given the final high LDL cholesterol values that were achieved in this study on heterozygous familial hypercholesterolemic patients which has very little relevance to the general population we see daily. |
| 10. | 2/3/2008 6:02:00 AM | the LDL did drop more with vytorin than zocor in ENHANCE |
| 11. | 2/4/2008 2:00:00 PM | This is incorrect. ENHANCE showed Vytorin lowered LDL more than simvastatin alone, 58% versus 41% p < 0.01, |