Comment Summary

The Vytorin-ENHANCE study was done on patients with a severe form of familial hypercholesterolemia that were previously being treated for elevated cholesterol with other agents. Can the results of such a study be applicable to patients who have a non-familial elevated cholesterol secondary to age, obesity, poor diet and sedentary life style?
#	Response Date	Other (please specify)
1.	4/22/2008 5:50:00 PM	the findings are relevant to the discussion
2.	4/22/2008 6:33:00 PM	not certain
3.	4/22/2008 7:13:00 PM	unknown
4.	4/22/2008 9:09:00 PM	uncertain
5.	4/22/2008 10:03:00 PM	no
6.	4/22/2008 11:33:00 PM	Not known, yet to be determined.
7.	4/23/2008 1:46:00 AM	Not sure but until it is proven to NOT BE HARMFUL (in terms of plaque growth and clinical outcomes) in other patient populations why use it when the statins have proven efficacy
8.	4/23/2008 1:46:00 AM	Uncertain at this point
9.	4/23/2008 11:32:00 AM	Not certain
10.	4/23/2008 3:11:00 PM	not sure
11.	4/24/2008 4:30:00 PM	uncertain
12.	4/25/2008 12:18:00 AM	with caution
13.	5/2/2008 1:52:00 AM	Main lack of applicability has to do with extensive prior treatment and low baseline CIMT