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The ENHANCE study was done on patients with a severe form of familial hypercholesterolemia. Can the results of such a study be applicable to patients who have a non-familial elevated cholesterol secondary to age, obesity, poor diet and lack of exercise?
#	Response Date	Other (please specify)
1.	1/30/2008 9:58:00 PM	Depends on how high cholesterol is
2.	1/30/2008 10:08:00 PM	Those patients werealready on a statin, ergo zocor + zetia study design seems flawed.
3.	1/30/2008 10:24:00 PM	not sure
4.	1/31/2008 3:19:00 AM	Diet may play a much greater role in the non-familial patients.
5.	1/31/2008 3:59:00 PM	Study results are applicable to the population studied, not necessarily any other population.
6.	1/31/2008 4:51:00 PM	Zetia blocks the cholestrol you eat - which in the study group was probably a lower % of their cholesterol burden
7.	2/1/2008 3:19:00 AM	Not sure without studies
8.	2/3/2008 6:02:00 AM	to some extent yes
9.	2/4/2008 2:00:00 PM	for LDL lowering yes, for carotid ultrasound measurements no.